BDBM631370 2-[(4-Acetylpiperazin-1-yl)methyl]-6-(2-chloro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid::US20230348398, Example 16

SMILES CC(=O)N1CCN(Cc2nc3c(C(=O)O)cc(-c4ccc(C)cc4Cl)cc3[nH]2)CC1

InChI Key InChIKey=SCISMQWVRMAULX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 631370   

TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 631370BDBM631370(US20230348398, Example 16 | 2-[(4-Acetylpiperazin-...)
Affinity DataIC50: 1.51E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent