BDBM631374 6-(2-Chloro-4-methylphenyl)-2-[(3-oxopiperazin-1-yl)methyl]-1H-benzimidazole-4-carboxylic acid::US20230348398, Example 20

SMILES Cc1ccc(-c2cc(C(=O)O)c3nc(CN4CCNC(=O)C4)[nH]c3c2)c(Cl)c1

InChI Key InChIKey=SZMVIGFACYDERA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 631374   

TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 631374BDBM631374(US20230348398, Example 20 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 590nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent