BDBM631615 US20230348424, Example 198

SMILES C[C@@H](NC(=O)c1cn([C@H]2[C@H](C)C2(F)F)c(=O)cc1N[C@@H]1[C@H]2CN(C)C[C@@H]12)c1cccc(c1F)C(F)(F)F

InChI Key InChIKey=YUOWHAVBYQQPPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 631615   

LigandPNGBDBM631615(US20230348424, Example 198)
Affinity DataIC50: 3.41nMAssay Description:Inhibition of the SOS 1:KRAS interaction was measured using purified GST-tagged KRAS (res. 1-169, G12C, purified based on Hillig, et al., Proc Natl A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent