BDBM631838 US20230348426, Example 108

SMILES COc1ccc(cc1)[C@@H]1CN(C(=O)[C@H]1NC(=O)c1ccc(OC(F)(F)F)cc1)c1c(C)ccn(CCO)c1=O

InChI Key InChIKey=KDEUTNAJDRWTSC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 631838   

TargetfMet-Leu-Phe receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM631838(US20230348426, Example 108)
Affinity DataEC50:  0.400nMAssay Description: A mixture of forskolin (5 M final for FPR2 or 10 M final for FPR1) and IBMX (200 M final) were added to 384-well Proxiplates (Perkin-Elmer) pre-dott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetN-formyl peptide receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM631838(US20230348426, Example 108)
Affinity DataEC50:  2.90nMAssay Description: A mixture of forskolin (5 M final for FPR2 or 10 M final for FPR1) and IBMX (200 M final) were added to 384-well Proxiplates (Perkin-Elmer) pre-dott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent