BDBM63202 MLS000585637::N-(2,4-difluorophenyl)-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide::N-[2,4-bis(fluoranyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide::SMR000204200::cid_3525351

SMILES Cc1cccc(-c2nn(CC(=O)Nc3ccc(C(=O)OCCN(C)C)nc3)cc2-c2ccnc3ccccc23)n1

InChI Key InChIKey=YNCWEOYUIKKWMT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 63202   

TargetTGF-beta receptor type-1(Human)
Agomab Spain S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 63202BDBM63202(2-(dimethylamino)ethyl 5-(2-(3-(6-methylpyridin-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 63202BDBM63202(2-(dimethylamino)ethyl 5-(2-(3-(6-methylpyridin-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent