BDBM63218 (5E)-3-(3-chlorophenyl)-5-[[1-(4-methoxyphenyl)-2-pyrrolyl]methylidene]imidazolidine-2,4-dione::(5E)-3-(3-chlorophenyl)-5-[[1-(4-methoxyphenyl)pyrrol-2-yl]methylene]hydantoin::(5E)-3-(3-chlorophenyl)-5-[[1-(4-methoxyphenyl)pyrrol-2-yl]methylidene]imidazolidine-2,4-dione::3-(3-Chloro-phenyl)-5-[1-[1-(4-methoxy-phenyl)-1H-pyrrol-2-yl]-meth-(E)-ylidene]-imidazolidine-2,4-dione::MLS000331821::SMR000221234::cid_5913801

SMILES CNCCOC(=O)c1cc(F)cc(NC(=O)Cn2cc(-c3ccnc4ccccc34)c(-c3cccc(C)n3)n2)c1

InChI Key InChIKey=MLTNSRPISPULAW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 63218   

TargetTGF-beta receptor type-1(Human)
Agomab Spain S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 63218BDBM63218(2-(methylamino)ethyl 3-fluoro-5-(2-(3-(6-methylpyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 63218BDBM63218(2-(methylamino)ethyl 3-fluoro-5-(2-(3-(6-methylpyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent