BDBM63224 5-Bromo-3-phenyl-1H-indole-2-carboxylic acid [1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide::5-bromanyl-N'-[(4-oxidanylidenecyclohexa-2,5-dien-1-ylidene)methyl]-3-phenyl-1H-indole-2-carbohydrazide::5-bromo-N'-[(4-ketocyclohexa-2,5-dien-1-ylidene)methyl]-3-phenyl-1H-indole-2-carbohydrazide::5-bromo-N'-[(4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-3-phenyl-1H-indole-2-carbohydrazide::5-bromo-N'-[(4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-3-phenyl-1H-indole-2-carbohydrazide::MLS000591411::SMR000218982::cid_5921226

SMILES Cc1cccc(-c2nn(CC(=O)Nc3cc(F)cc(C(=O)OCC4CCNCC4)c3)cc2-c2ccnc3ccccc23)n1

InChI Key InChIKey=GFNVXYLNGIDIKC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63224   

TargetTGF-beta receptor type-1(Human)
Agomab Spain S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 63224BDBM63224(piperidin-4-ylmethyl 3-fluoro-5-(2-(3-(6-methylpyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent