BDBM63233 1-[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]-3-methyl-1-(3,4,5-trimethoxybenzyl)thiourea::1-[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]-3-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]thiourea::MLS000696884::SMR000237416::cid_2157837

SMILES c1nc2c(Nc3ccc(N4CCOCC4)cc3)nc(-c3ccc4cc[nH]c4c3)cn2n1

InChI Key InChIKey=SQGPVRYEOOPCDV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63233   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63233BDBM63233(6-(1H-indol-6-yl)-N-(4-morpholinophenyl)-[1,2,4]tr...)
Affinity DataIC50: 50nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent