BDBM63243 2-(5-hydroxy-4-keto-2-phenyl-chromen-7-yl)oxyacetic acid tert-butyl ester::2-[(5-hydroxy-4-oxo-2-phenyl-1-benzopyran-7-yl)oxy]acetic acid tert-butyl ester::MLS000374372::SMR000242288::cid_5429127::tert-butyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate::tert-butyl 2-(5-oxidanyl-4-oxidanylidene-2-phenyl-chromen-7-yl)oxyethanoate

SMILES COCCN1CCN(c2ccc(Nc3nc(-c4ccc5cn[nH]c5c4)cn4ncnc34)cc2OC)CC1

InChI Key InChIKey=TWBYICCJKQMSBJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63243   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63243BDBM63243(6-(1H-indazol-6-yl)-N-(3-methoxy-4-(4-(2-methoxyet...)
Affinity DataIC50: 50nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent