BDBM63248 2,4-bis(oxidanyl)benzohydrazide::2,4-dihydroxybenzohydrazide::MLS000696965::SMR000237724::cid_166785

SMILES COc1cc(Nc2nc(-c3ccc4cn[nH]c4c3)cn3ncnc23)ccc1N1CCN(C2CC2)CC1

InChI Key InChIKey=GOPUHTXVZGIOHN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63248   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63248BDBM63248(N-(4-(4-cyclopropylpiperazin-1-yl)-3-methoxyphenyl...)
Affinity DataIC50: 50nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent