BDBM63254 1-(2-fluorophenyl)-1-cyclopentanecarboxylic acid [2-oxo-2-(4-sulfamoylanilino)ethyl] ester::1-(2-fluorophenyl)cyclopentanecarboxylic acid [2-keto-2-(4-sulfamoylanilino)ethyl] ester::MLS000393262::SMR000243686::[2-oxidanylidene-2-[(4-sulfamoylphenyl)amino]ethyl] 1-(2-fluorophenyl)cyclopentane-1-carboxylate::[2-oxo-2-(4-sulfamoylanilino)ethyl] 1-(2-fluorophenyl)cyclopentane-1-carboxylate::cid_2389343

SMILES Nc1cncc(-c2cn3ncnc3c(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)n1

InChI Key InChIKey=PGPJEEIVJCYMFI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63254   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63254BDBM63254(6-(6-aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piper...)
Affinity DataIC50: 50nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2026
Entry Details
US Patent