BDBM63258 1-(1,3-benzothiazol-2-ylamino)-3-phenyl-urea::1-(1,3-benzothiazol-2-ylamino)-3-phenylurea::MLS000722223::SMR000235919::cid_4584673

SMILES CC1(C)Oc2cc(-c3cn4ncnc4c(Nc4ccc(N5CCOCC5)cc4)n3)ccc2NC1=O

InChI Key InChIKey=SYNQUXOYTFXISC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63258   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63258BDBM63258(2,2-dimethyl-7-(8-((4-morpholinophenyl)amino)-[1,2...)
Affinity DataIC50: 275nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent