BDBM63259 5-nitro-2-thiophenecarboxylic acid [2-(7-ethyl-1H-indol-3-yl)-2-oxoethyl] ester::5-nitrothiophene-2-carboxylic acid [2-(7-ethyl-1H-indol-3-yl)-2-keto-ethyl] ester::MLS000334288::SMR000249046::[2-(7-ethyl-1H-indol-3-yl)-2-oxidanylidene-ethyl] 5-nitrothiophene-2-carboxylate::[2-(7-ethyl-1H-indol-3-yl)-2-oxoethyl] 5-nitrothiophene-2-carboxylate::cid_2499208

SMILES c1nc2c(Nc3ccc(N4CCN(C5COC5)CC4)cc3)nc(-c3ccc4cc[nH]c4c3)cn2n1

InChI Key InChIKey=PXWQEPOPSFZYOW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63259   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63259BDBM63259(6-(1H-indol-6-yl)-N-(4-(4-(oxetan-3-yl)piperazin-1...)
Affinity DataIC50: 50nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent