BDBM63260 MLS000705968::N'-[(5-bromo-2-furyl)methylene]-2,3-dihydro-1,4-benzodioxine-6-carbohydrazide::N-[(5-bromanylfuran-2-yl)methylideneamino]-2,3-dihydro-1,4-benzodioxine-6-carboxamide::N-[(5-bromo-2-furanyl)methylideneamino]-2,3-dihydro-1,4-benzodioxin-6-carboxamide::N-[(5-bromo-2-furyl)methyleneamino]-2,3-dihydro-1,4-benzodioxin-6-carboxamide::N-[(5-bromofuran-2-yl)methylideneamino]-2,3-dihydro-1,4-benzodioxine-6-carboxamide::SMR000225450::cid_1237232

SMILES FC(F)(F)Oc1cc(Nc2nc(-c3ccc4cn[nH]c4c3)cn3ncnc23)ccc1N1CCOCC1

InChI Key InChIKey=PFEWOUJKCIQNHM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63260   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63260BDBM63260(6-(1H-indazol-6-yl)-N-(4-morpholino-3-(trifluorome...)
Affinity DataIC50: 275nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent