BDBM63263 MLS000681152::N-(4-nitrophenyl)-4-phenyl-4-oxanecarboxamide::N-(4-nitrophenyl)-4-phenyl-oxane-4-carboxamide::N-(4-nitrophenyl)-4-phenyl-tetrahydropyran-4-carboxamide::N-(4-nitrophenyl)-4-phenyloxane-4-carboxamide::N-(4-nitrophenyl)-4-phenyltetrahydro-2H-pyran-4-carboxamide::SMR000269420::cid_2901255

SMILES FC(F)Oc1cc(Nc2nc(-c3ccc4cn[nH]c4c3)cn3ncnc23)ccc1N1CCOCC1

InChI Key InChIKey=ZSRGGXMQORJDHF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63263   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63263BDBM63263(N-(3-(difluoromethoxy)-4-morpholinophenyl)-6-(1H-i...)
Affinity DataIC50: 50nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent