BDBM63267 MLS000683392::N'-[(4-bromo-5-methyl-2-furyl)methylene]-2-(2-methyl-1,3-dioxolan-2-yl)acetohydrazide::N-[(4-bromanyl-5-methyl-furan-2-yl)methylideneamino]-2-(2-methyl-1,3-dioxolan-2-yl)ethanamide::N-[(4-bromo-5-methyl-2-furanyl)methylideneamino]-2-(2-methyl-1,3-dioxolan-2-yl)acetamide::N-[(4-bromo-5-methyl-2-furyl)methyleneamino]-2-(2-methyl-1,3-dioxolan-2-yl)acetamide::N-[(4-bromo-5-methylfuran-2-yl)methylideneamino]-2-(2-methyl-1,3-dioxolan-2-yl)acetamide::SMR000267857::cid_877962

SMILES CC1(O)CCN(c2ccc(Nc3nc(-c4ccc5cn[nH]c5c4)cn4ncnc34)cc2)CC1

InChI Key InChIKey=YWCRCJKQQXAOLG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63267   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63267BDBM63267(1-(4-((6-(1H-indazol-6-yl)-[1,2,4]triazolo[1,5-a]p...)
Affinity DataIC50: 50nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent