BDBM63268 2-[2-(4-chlorophenyl)sulfonylethyl]-1H-benzimidazole::2-{2-[(4-chlorophenyl)sulfonyl]ethyl}-1H-benzimidazole::MLS000683389::SMR000267852::cid_589050

SMILES c1nc2c(Nc3ccc(N4CC5(COC5)C4)cc3)nc(-c3ccc4cc[nH]c4c3)cn2n1

InChI Key InChIKey=QGFKKILHGCDHML-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63268   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63268BDBM63268(N-(4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)phenyl)-6-(...)
Affinity DataIC50: 50nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent