BDBM63280 1-[2-(4-bromanylphenoxy)ethoxy]-3-[4-(4-methoxyphenyl)piperazin-1-yl]propan-2-ol;hydrochloride::1-[2-(4-bromophenoxy)ethoxy]-3-[4-(4-methoxyphenyl)-1-piperazinyl]-2-propanol;hydrochloride::1-[2-(4-bromophenoxy)ethoxy]-3-[4-(4-methoxyphenyl)piperazin-1-yl]propan-2-ol;hydrochloride::1-[2-(4-bromophenoxy)ethoxy]-3-[4-(4-methoxyphenyl)piperazino]propan-2-ol;hydrochloride::MLS000698838::SMR000225364::cid_15944964

SMILES COc1cc(Nc2nc(-c3cnc4c(c3)OC(C)(C)C(=O)N4)cn3ncnc23)ccc1N1CCOCC1

InChI Key InChIKey=NJMDKZBARPNHDH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63280   

TargetTyrosine-protein kinase SYK(Human)
Nanjing Ruijie Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63280BDBM63280(7-(8-((3-methoxy-4-morpholinophenyl)amino)-[1,2,4]...)
Affinity DataIC50: 275nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2026
Entry Details
US Patent