BDBM633210 US20230348495, Example 13

SMILES Oc1cc(C(=O)N2Cc3nc(OCC4(CN5CCOCC5)CC4)nc(N4CC5CCC(C4)N5)c3C2)c2c(I)cccc2c1

InChI Key InChIKey=NNVDLLGHCFWECQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633210   

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633210(US20230348495, Example 13)
Affinity DataIC50: 5.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent