BDBM633218 US20230348495, Example 15

SMILES CN(C)CC1(COc2nc(N3CC4CCC(C3)N4)c3ccc(c(F)c3n2)-c2cc(O)cc3ccccc23)CC1

InChI Key InChIKey=PICWWXWWCFHXEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633218   

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633218(US20230348495, Example 15)
Affinity DataIC50: 4.70nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent