BDBM633225 US20230348495, Example 19

SMILES CCc1cc2c(nc(OCC3(CN(C)C)CC3)nc2c(F)c1-c1cc(O)cc2ccccc12)N1CC2CCC(C1)N2

InChI Key InChIKey=DEQXDBPDVWTGKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633225   

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633225(US20230348495, Example 19)
Affinity DataIC50: 7.10nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent