BDBM633226 US20230348495, Example 20

SMILES CN(C)CC1(COc2nc3CN(CCc3c(n2)N2C[C@@H]3CC[C@H]2CN3)c2cc(O)cc3cccc(Br)c23)CC1

InChI Key InChIKey=ZNJOYPGREVAOTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633226   

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633226(US20230348495, Example 20)
Affinity DataIC50: 3nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent