BDBM633231 US20230348495, Example 25

SMILES Ic1cccc2cccc(N3CCc4c(C3)nc(OCC3(CN5CCOCC5)CC3)nc4N3CC4CCC(C3)N4)c12

InChI Key InChIKey=PDLJOUFUBCEFGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633231   

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633231(US20230348495, Example 25)
Affinity DataIC50: 39.8nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent