BDBM633238 US20230348495, Example 32

SMILES CO[C@@H]1C[C@@H](COc2nc3CN(CCc3c(n2)N2CC3CCC(C2)N3)c2cc(O)cc3cccc(Br)c23)N(C)C1

InChI Key InChIKey=MZMUFLIJNJRKRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633238   

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633238(US20230348495, Example 32)
Affinity DataIC50: 3.20nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent