BDBM633239 US20230348495, Example 33

SMILES Oc1cc(C2Cc3nc(OCC4(CN5CCOCC5)CC4)nc(N4CC5CCC(C4)N5)c3CO2)c2c(cccc2c1)C#C

InChI Key InChIKey=PBYDLNVDYBRPHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633239   

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633239(US20230348495, Example 33)
Affinity DataIC50: 11.3nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent