BDBM633259 Preparation of 2-[(R)-3-(8-phenyl)octanoyloxytetradecanoylamino]ethyl 2,3-di-[(R)-3-(8-phenyl)octanoyloxytetradecanoylamino]-2,3-dideoxy-4-O-phosphono-β-D-allopyranoside triethylammonium Salt ::US11458151, Compound 8

SMILES CCCCCCCCCCC[C@H](CC(=O)NCCO[C@@H]1OC(CO)[C@@H](OP(O)(O)=O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCc2ccccc2)C1NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCc1ccccc1)OC(=O)CCCCCCCc1ccccc1

InChI Key InChIKey=MUJJAQHVQWTOBE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633259   

TargetToll-like receptor 4(Human)
Inimmune

US Patent
LigandPNGBDBM633259(US11458151, Compound 8 | Preparation of 2-[(R)-3-(...)
Affinity DataEC50:  4.99nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2023
Entry Details
US Patent