BDBM633472 N-(4-((6,7-dimethoxy-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phenyl)sulfamide hydrochloride::US20230159469, Example 182

SMILES COc1cc2c(Cc3ccc(NS(N)(=O)=O)cc3)n[nH]c(=O)c2cc1OC

InChI Key InChIKey=QPVNZUGJCGHUTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 633472   

LigandPNGBDBM633472(N-(4-((6,7-dimethoxy-4-oxo-3,4-dihydrophthalazin-1...)
Affinity DataIC50:  69nMAssay Description:Inhibition of recombinant human ENPP1 using cGAMP as substrate assessed as inhibition of cGAMP hydrolysis preincubated for 5 to 10 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM633472(N-(4-((6,7-dimethoxy-4-oxo-3,4-dihydrophthalazin-1...)
Affinity DataIC50: <1.00E+3nMAssay Description:ENPP1 hydrolyzes nucleotides or nucleotide derivatives to produce nucleoside -5′-monophosphate and pyrophosphate. in addition, ENPP1 hydrolyzes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent