BDBM633474 N-methyl-N-(4-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phenyl)sulfamide hydrochloride::US20230159469, Example 184

SMILES CN(c1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1)S(N)(=O)=O

InChI Key InChIKey=UAVSNVQAIAZYFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 633474   

LigandPNGBDBM633474(N-methyl-N-(4-((4-oxo-3,4-dihydrophthalazin-1-yl)m...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of recombinant human ENPP1 using cGAMP as substrate assessed as inhibition of cGAMP hydrolysis preincubated for 5 to 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandPNGBDBM633474(N-methyl-N-(4-((4-oxo-3,4-dihydrophthalazin-1-yl)m...)
Affinity DataIC50: 5.50E+3nMAssay Description:ENPP1 hydrolyzes nucleotides or nucleotide derivatives to produce nucleoside -5′-monophosphate and pyrophosphate. in addition, ENPP1 hydrolyzes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent