BDBM633491 3-(6-amino-1-(4-amino-2-fluorobenzyl)-1H-pyrazolo[3,4-d]pyrimidine-4-yl)benzonitrile ::US11806350, Compound 209::US12606564, Compound 209

SMILES Nc1ccc(Cn2ncc3c(nc(N)nc23)-c2cccc(c2)C#N)c(F)c1

InChI Key InChIKey=RRMBOBGRBMMUOC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 633491   

TargetAdenosine receptor A2a(Human)
Ildong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 633491BDBM633491(US11806350, Compound 209 | 3-(6-amino-1-(4-amino-2...)
Affinity DataKi: <20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Ildong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 633491BDBM633491(US11806350, Compound 209 | 3-(6-amino-1-(4-amino-2...)
Affinity DataKi: <100nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Ildong Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633491BDBM633491(US11806350, Compound 209 | 3-(6-amino-1-(4-amino-2...)
Affinity DataKi:  110nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Ildong Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633491BDBM633491(US11806350, Compound 209 | 3-(6-amino-1-(4-amino-2...)
Affinity DataKi:  550nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent