BDBM633503 6-[6-amino-1-[(4-amino-2,6-difluoro-phenyl)methyl]pyrazolo[3,4-d]pyrimidine-4-yl]pyridine-2-carbonitrile ::US11806350, Compound 223::US12606564, Compound 223
SMILES Nc1cc(F)c(Cn2ncc3c(nc(N)nc23)-c2cccc(n2)C#N)c(F)c1
InChI Key InChIKey=AMCJXWMORREWLX-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 633503
Affinity DataKi: <20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair