BDBM633504 2-[6-amino-1-[(4-amino-2,6-difluoro-phenyl)methyl]pyrazolo[3,4-d]pyrimidine-4-yl]pyridine-4-carbonitrile ::US11806350, Compound 224::US12606564, Compound 224
SMILES Nc1cc(F)c(Cn2ncc3c(nc(N)nc23)-c2cc(ccn2)C#N)c(F)c1
InChI Key InChIKey=YJVPPONEOQQPAH-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 633504
Affinity DataKi: 110nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair