BDBM633513 5-(6-amino-1-(2,6-difluorobenzyl)-1H-pyrazolo[3,4-d]pyrimidine-4-yl)nicotinonitrile ::US11806350, Compound 233

SMILES Nc1nc(-c2cncc(c2)C#N)c2cnn(Cc3c(F)cccc3F)c2n1

InChI Key InChIKey=YQAKAGUMJOSZSI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 633513   

TargetAdenosine receptor A1(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM633513(US11806350, Compound 233 | 5-(6-amino-1-(2,6-diflu...)
Affinity DataKi:  600nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM633513(US11806350, Compound 233 | 5-(6-amino-1-(2,6-diflu...)
Affinity DataKi:  5.50E+3nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent