BDBM633958 US11807649, Compound 33

SMILES Cc1cc(Nc2ncnc3cc4OC[C@@H]5CN(CCN5C(=O)C=C)c4nc23)ccc1Oc1ccn2ccnc2c1

InChI Key InChIKey=RFABPKSSVXQXLK-FQEVSTJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 633958   

TargetEpidermal growth factor receptor(Human)
Enliven Therapeutics

US Patent
LigandPNGBDBM633958(US11807649, Compound 33)
Affinity DataIC50:  164nMAssay Description:Enzyme-linked immunosorbent assays (ELISA) were performed to measure phosphorylated EGFR levels using A431 cells (10% FBS). A431 (1.0*104 cells/40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetReceptor tyrosine-protein kinase erbB-2(Human)
Enliven Therapeutics

US Patent
LigandPNGBDBM633958(US11807649, Compound 33)
Affinity DataIC50:  16.8nMAssay Description:Enzyme-linked immunosorbent assays (ELISA) were performed to measure phosphorylated ERBB2 levels. A capture antibody able to detect phosphorylated an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent