BDBM634115 US20230357248, Example 6

SMILES Clc1cc(Oc2ccccc2)ccc1C(=O)c1c[nH]c2ncnc(N[C@@H]3CC[C@@H](CC#N)OC3)c12

InChI Key InChIKey=UMHGKWWZSMLLSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634115   

TargetTyrosine-protein kinase BTK [C481S](Human)
Medshine Discovery

US Patent
LigandPNGBDBM634115(US20230357248, Example 6)
Affinity DataIC50: 6.5nMAssay Description:The specific assay process of BTK enzyme activity assay is as follows: Buffer: 20 mM 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid (Hepes) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent