BDBM634344 4,5-difluoro-8,14-dioxa-10,19,20-::US20230357269, Example 29

SMILES O=C1NCCCOc2ccc3[nH]nc(c3c2)-c2cc(F)c(F)c(c2)CO1

InChI Key InChIKey=OAAMEEOOCJSIOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634344   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Les Laboratoires Servier

US Patent
LigandChemical structure of BindingDB Monomer ID 634344BDBM634344(US20230357269, Example 29 | 4,5-difluoro-8,14-diox...)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent