BDBM634348 1-{9-oxo-8,14-dioxa-10,19,20-triazatetra::US20230357269, Example 33

SMILES N#CC1CCN(c2cc3cc(c2)-c2n[nH]c4ccc(cc24)OCCCNC(=O)OC3)CC1

InChI Key InChIKey=QWABWDLJLXVTOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634348   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 634348BDBM634348(US20230357269, Example 33 | 1-{9-oxo-8,14-dioxa-10...)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent