BDBM634374 4-[(3S)-3-hydroxypyrrolidin-1-yl]-8,14-dioxa-::US20230357269, Example 59

SMILES O=C1NCCCOc2ccc3[nH]nc(c3c2)-c2cc(cc(N3CC[C@H](O)C3)c2)CO1

InChI Key InChIKey=AAJISJWUDFORLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634374   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 634374BDBM634374(US20230357269, Example 59 | 4-[(3S)-3-hydroxypyrro...)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent