BDBM635395 1-Tert-butyl-5-fluoro-N-{2-fluoro-4-methyl-5-[8- (morpholin-4-yl)imidazo[1,2-a]pyridin-6- yl]phenyl}pyrazole-4-carboxamide::US11814384, Example 103::US11814384, Example 163

SMILES Cc1cc(F)c(NC(=O)c2cnn(c2F)C(C)(C)C)cc1-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=FICFPZFSYWTDQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 635395   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635395(US11814384, Example 103 | 1-Tert-butyl-5-fluoro-N-...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635395(US11814384, Example 103 | 1-Tert-butyl-5-fluoro-N-...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent