BDBM635399 2-(1,1-difluoropropan-2-yl)-N-(2-fluoro-4- methyl-5-(8-morpholinoimidazo[1,2-a]pyridin-6- yl)phenyl)isonicotinamide::US11814384, Example 113::US11814384, Example 114

SMILES CC(C(F)F)c1cc(ccn1)C(=O)Nc1cc(c(C)cc1F)-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=QDAJXPQCKRYAIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 635399   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635399(US11814384, Example 113 | US11814384, Example 114 ...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635399(US11814384, Example 113 | US11814384, Example 114 ...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent