BDBM635402 3-fluoro-N-(2-fluoro-4-methyl-5-(8- morpholinoimidazo[1,2-a]pyridin-6-yl)phenyl)-4- isopropylpyrrolidine-1-carboxamide::US11814384, Example 119::US11814384, Example 120::US11814384, Example 121

SMILES CC(C)C1CN(CC1F)C(=O)Nc1cc(c(C)cc1F)-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=STNVCVSJKRBLKF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 635402   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635402(US11814384, Example 119 | 3-fluoro-N-(2-fluoro-4-m...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635402(US11814384, Example 119 | 3-fluoro-N-(2-fluoro-4-m...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635402(US11814384, Example 119 | 3-fluoro-N-(2-fluoro-4-m...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent