BDBM635412 1-(Tert-butyl)-N-(2-fluoro-4-methyl-5-(2-methyl- 8-morpholinoimidazo[1,2-a]pyridin-6-yl)phenyl)- 1H-imidazole-4-carboxamide::US11814384, Example 140

SMILES Cc1cn2cc(cc(N3CCOCC3)c2n1)-c1cc(NC(=O)c2cn(cn2)C(C)(C)C)c(F)cc1C

InChI Key InChIKey=WLCBFEVUBACZEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635412   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635412(1-(Tert-butyl)-N-(2-fluoro-4-methyl-5-(2-methyl- 8...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent