BDBM635416 1-Tert-butyl-2-fluoro-N-{2-fluoro-4-methyl-5-[2- methyl-8-(morpholin-4-yl)imidazo[1,2-a]pyridin- 6-yl]phenyl}imidazole-4-carboxamide::US11814384, Example 148

SMILES Cc1cn2cc(cc(N3CCOCC3)c2n1)-c1cc(NC(=O)c2cn(c(F)n2)C(C)(C)C)c(F)cc1C

InChI Key InChIKey=AAJVULSBTLDJSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635416   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635416(1-Tert-butyl-2-fluoro-N-{2-fluoro-4-methyl-5-[2- m...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
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Date in BDB:
1/8/2024
Entry Details
US Patent