BDBM635417 1-Tert-butyl-N-{4-chloro-2-fluoro-5-[8- (morpholin-4-yl)imidazo[1,2-a]pyridin-6- yl]phenyl}-2-fluoroimidazole-4-carboxamide::US11814384, Example 151

SMILES CC(C)(C)n1cc(nc1F)C(=O)Nc1cc(c(Cl)cc1F)-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=CIYGZAUAOLMYEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635417   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635417(1-Tert-butyl-N-{4-chloro-2-fluoro-5-[8- (morpholin...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
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Date in BDB:
1/8/2024
Entry Details
US Patent