BDBM635423 1-{Bicyclo[1.1.1]pentan-1-yl}-N-{2-fluoro-4- methyl-5-[8-(morpholin-4-yl)imidazo[1,2- a]pyridin-6-yl]phenyl}pyrazole-4-carboxamide::US11814384, Example 164

SMILES Cc1cc(F)c(NC(=O)c2cnn(c2)C23CC(C2)C3)cc1-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=FOECTKPGCUWGLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635423   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635423(1-{Bicyclo[1.1.1]pentan-1-yl}-N-{2-fluoro-4- methy...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent