BDBM635424 N-{2-fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo[1,2-a]pyridin-6-yl]phenyl}-2- (pyrrolidin-1-yl)pyridine-4-carboxamide::US11814384, Example 166

SMILES Cc1cc(F)c(NC(=O)c2ccnc(c2)N2CCCC2)cc1-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=HGWRFYGMRNLXFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635424   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635424(N-{2-fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
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Date in BDB:
1/8/2024
Entry Details
US Patent