BDBM635429 2-Tert-butyl-N-{4-methyl-3-[8-(morpholin-4- yl)imidazo[1,2-a]pyridin-6-yl]phenyl}-1,3- oxazole-5-carboxamide::US11814384, Example 185

SMILES Cc1ccc(NC(=O)c2cnc(o2)C(C)(C)C)cc1-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=OMJXFWRGGUGYHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635429   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635429(2-Tert-butyl-N-{4-methyl-3-[8-(morpholin-4- yl)imi...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
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Date in BDB:
1/8/2024
Entry Details
US Patent