BDBM635433 N-(1-tert-butylpyrazol-4-yl)-2-fluoro-4-methyl-5- [8-(morpholin-4-yl)imidazo[1,2-a]pyridin-6- yl]benzamide::US11814384, Example 204

SMILES Cc1cc(F)c(cc1-c1cc(N2CCOCC2)c2nccn2c1)C(=O)Nc1cnn(c1)C(C)(C)C

InChI Key InChIKey=DYOWUERYFYKTIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635433   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635433(N-(1-tert-butylpyrazol-4-yl)-2-fluoro-4-methyl-5- ...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
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Date in BDB:
1/8/2024
Entry Details
US Patent