BDBM635435 N-{2-Fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo[1,2-a]pyridin-6-yl]phenyl}-1- isopropylpyrrolo[2,3-b]pyridine-4-carboxamid::US11814384, Example 206

SMILES CC(C)n1ccc2c(ccnc12)C(=O)Nc1cc(c(C)cc1F)-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=HQONIDXZDUDYLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635435   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635435(N-{2-Fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
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Date in BDB:
1/8/2024
Entry Details
US Patent