BDBM635586 US20230364079, Example 6

SMILES Nc1nccn2c(nc(-c3ccc(Oc4cccc(OC(F)(F)F)c4F)cc3)c12)C1CCC(CO)OC1

InChI Key InChIKey=PXXAOMCMAKZROR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 635586   

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635586(US20230364079, Example 6)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635586(US20230364079, Example 6)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent