BDBM636167 US20230365541, Compound 9, isomer 2

SMILES CO[C@H]1C[C@H](N[C@H]2CC[C@@H](C3(C)Oc4c(Cl)cc(C(=O)NCc5c(SC)cc(C)[nH]c5=O)c(C)c4O3)CC2)C1

InChI Key InChIKey=CIJHVAWUSUTLMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636167   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Haisco Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 636167BDBM636167(US20230365541, Compound 9, isomer 2)
Affinity DataIC50: 0.480nMAssay Description:The compounds were dissolved in DMSO, formulated into 10 mM solutions and serially diluted with DMSO to obtain 100-fold the final concentration. 200 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent